0700 Parasomnia-related homicides: A systematic review and a critical analysis of the medical literature

Abstract Introduction Cases of homicide allegedly committed during sleep have been described since ancient history. The strongest link between violence and disorders is represented by the so-called parasomnias, a group characterized episodic undesirable behaviors and/or mental experiences that arise sleep. Methods We conducted systematic search according to PRISMA guidelines with 4 different engines (Pubmed, Scopus, Embase Cochrane) aim gathering critically evaluating all cases homicides associated parasomnias Results identified over 30 parasomnia episode. diagnosis was NREM for except one, which received REM-sleep behavior disorder (RBD). Victims were more often female family members, killed firearms or sharp objects, usually nearby bed. Aggressors reported delusional/hallucinatory their episodes rarely made any effort cover up crime. In majority cases, no objective data available. Only minority patients had positive childhood court judgement not uniform across cases. Conclusion Although rarely, could be episodes. Despite being frequently violent behaviors, RBD less likely led fatal aggressions. According observed subjective reports current neurophysiological knowledge, are only partially conscious largely disconnected from external environment, considered guilty actions. Support (if any) None